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S M Sebti Selected Research

CEP 1612

2/2001CEP1612, a dipeptidyl proteasome inhibitor, induces p21WAF1 and p27KIP1 expression and apoptosis and inhibits the growth of the human lung adenocarcinoma A-549 in nude mice.

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S M Sebti Research Topics

Disease

15Neoplasms (Cancer)
11/2010 - 01/2000
4Lung Neoplasms (Lung Cancer)
07/2002 - 02/2001
2Carcinogenesis
11/2010 - 12/2000
1Prostatic Neoplasms (Prostate Cancer)
01/2014
1Neoplasm Metastasis (Metastasis)
01/2014
1Brain Neoplasms (Brain Tumor)
02/2007
1Multiple Myeloma
02/2003
1Fibrosarcoma
07/2002
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2001
1Inflammation (Inflammations)
10/2001
1Adenocarcinoma of Lung
02/2001
1Systemic Scleroderma (Systemic Sclerosis)
07/2000
1Adenoma (Adenomas)
01/2000
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2000

Drug/Important Bio-Agent (IBA)

10Farnesyltranstransferase (Farnesyltransferase)IBA
02/2007 - 01/2000
3Antineoplastic Agents (Antineoplastics)IBA
01/2014 - 12/2000
3geranylgeranyltransferase type-I (protein geranylgeranyltransferase)IBA
02/2007 - 12/2000
3FTI 277IBA
02/2003 - 01/2000
3TransferasesIBA
02/2003 - 07/2000
2Pharmaceutical PreparationsIBA
11/2010 - 02/2003
2Proteins (Proteins, Gene)FDA Link
12/2000 - 01/2000
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2000 - 01/2000
2GFB 111IBA
12/2000 - 10/2000
1myosin light chain 2IBA
01/2014
1triciribine phosphateIBA
11/2010
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
05/2007
1erythromycin propionate-N-acetylcysteinateIBA
05/2007
1pirbuterol (Maxair)FDA Link
05/2007
1beta-2 Adrenergic ReceptorsIBA
05/2007
1Adrenergic Receptors (Adrenergic Receptor)IBA
05/2007
1Histones (Histone)IBA
02/2007
1DAPIIBA
07/2002
1DNA (Deoxyribonucleic Acid)IBA
07/2002
1Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2001
1CytokinesIBA
10/2001
1InterleukinsIBA
10/2001
1CEP 1612IBA
02/2001
1Uridine Triphosphate (UTP)IBA
02/2001
1Proteasome InhibitorsIBA
02/2001
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
02/2001
1LipidsIBA
12/2000
1ras ProteinsIBA
12/2000
1Transforming Growth Factor beta (TGF-beta)IBA
11/2000
1Platelet-Derived Growth FactorIBA
10/2000
1CollagenIBA
07/2000
1Collagen Type I (Type I Collagen)IBA
07/2000
1Insulin (Novolin)FDA Link
06/2000
1Tyrosine (L-Tyrosine)FDA Link
01/2000
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
01/2000
1Codon (Codons)IBA
01/2000
1Phosphotransferases (Kinase)IBA
01/2000
1FTI 276IBA
01/2000
1Phosphatidylinositols (Phosphatidylinositol)IBA
01/2000
1PeptidomimeticsIBA
01/2000
14- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA
01/2000

Therapy/Procedure

4Therapeutics
11/2010 - 12/2000